Abstract submission deadline extended!

The deadline for abstract submissions has been extended untill August 15th, to give you the opportunity to share your latest results. Keep those abstracts coming!

The best poster presentation will receive a travel grant for ISSCR 2015 in Stockholm.

Low-grade chromosomal mosaicism in human somatic and embryonic stem cell populations

By Jacobs K et al. (Research Group Reproduction and Genetics, Vrije Universiteit Brussel)

In this study, the genetic content of 92 individual human cells, including fibroblasts, amniocytes and embryonic stem cells (hESCs) was investigated using single-cell array-based comparative genomic hybridization (aCGH). We find that human somatic and embryonic stem cell cultures show significant fractions of cells carrying unique megabase-scale chromosomal abnormalities, forming genetic mosaics that could not have been detected by conventional cytogenetic methods. Furthermore, fluorescent in situ hybridisation reveals an increased instability of the subtelomeric regions in hESC as compared to somatic cells. This genetic heterogeneity may have an impact on experimental results and, in the case of hESC, on their potential clinical use.

Read more at: http://www.nature.com/ncomms/2014/140627/ncomms5227/full/ncomms5227.html

Your article on this website!

Dear Belgian researchers,

 

Did you recently publish your work on stem cells? We would be very happy to display it on this website.

 

Just send an email to Mieke.Geens@vub.ac.be for further instructions.